Solid line = floor (spellings that unambiguously belong to the group). Shaded band up to the dashed edge = ceiling (the most it could reach if every ambiguous spelling counted here).
Serena has stayed fairly steady in American naming for generations. All-time it's been given to 66,130 U.S. babies, the 630th most common name by sound today, peaking at 2,001 in 2000, with 1,138 in 2025.
By sound, Serena also includes the spellings Sarina, Serina, Sirena.
Source: U.S. Social Security Administration, “National data” baby-names files (1880–2025).